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Apoptosis: Difference between revisions
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==Development== | ==Development== | ||
Origin of apoptosis is Greek. In Greek, apoptosis means falling off. Apoptosis is very necessary part of life cycle of organisms. Apoptosis is active process and plays important role in multicellular organisms. It regulates and adjusts population of cells. [http://www.celldeath.de/encyclo/aporev/aporev.htm] | Origin of apoptosis is Greek. In Greek, apoptosis means falling off. Apoptosis is very necessary part of life cycle of organisms. Apoptosis is active process and plays important role in multicellular organisms. It regulates and adjusts population of cells. [http://www.celldeath.de/encyclo/aporev/aporev.htm] | ||
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==Process== | ==Process== | ||
[[Image:Apoptosisprocess.jpg|250px|thumb|left|Apoptosis from irreparable mutation]] | |||
Cell signals control process of apoptosis. The cell signals are extracellular or intracellular. | |||
Hormones, growth factors, nitric oxicers, and cytokines are extracellular signals, and they cross plasma membranes. Intercellular signals are cell stress, cell suicide, heat, radiation, nutrient deprivation, and viral infection. [http://en.wikipedia.org/wiki/Apoptosis] | |||
===Pathways=== | ===Pathways=== | ||
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=====HIV===== | =====HIV===== | ||
HIV, Human Immunodeficiency Virus, has gene that cannot kill infected cells by apoptosis pathway. It happens when host’s immune system becomes weak. The host’s immune system becomes weak, because of wrong pathway of apoptosis programs to kill immune cells. In other words, number of immune cells is decreased by wrong pathway of apoptosis. [http://www.scq.ubc.ca/?p=350] | HIV, Human Immunodeficiency Virus, has gene that cannot kill infected cells by apoptosis pathway. It happens when host’s immune system becomes weak. The host’s immune system becomes weak, because of wrong pathway of apoptosis programs to kill immune cells. In other words, number of immune cells is decreased by wrong pathway of apoptosis. [http://www.scq.ubc.ca/?p=350] | ||
==Function of Apoptosis== | ==Function of Apoptosis== | ||
